Dr. Entcheva’s research published in Nature Communications
Dr. Emilia Entcheva's lab has developed a faster method, using optogenetics, to predict whether potential new drugs will cause heart arrhythmias. This new all-optical technology will accelerate the testing of new drugs and prevent future failures due to cardiotoxicity, using human cardiomyocytes. The team’s paper, “OptoDyCE as an Automated System for High-Throughput All-Optical Dynamic Cardiac Electrophysiology,” was published on March 10 in Nature Communications.
More information on the paper is available on ScienceDaily.
This is the second paper from the team in recent months (adding to dye-free imaging technology and optical “wave steering” in a recent Nature Photonics study) that offers innovative massively-parallel techniques for stem cell researchers in the cardiac field. Aleks Klimas, first author on the paper, hopes to pursue commercialization of the technology following her graduation.